A member asked:

In the event of excitotoxicity occurring after withdrawing from a benzodiazepine, would excitotoxicity occur before or after a seizure occurs, i.e. would a seizure indicate that the glutamate concentration had reached excitotoxic levels?

A doctor has provided 1 answer
Dr. Frank Amico Sr answered

Specializes in Addiction Medicine

Yes: Since the seizure would be caused by the excitotoxity phenomenon, it would need to occur before the seizure. So the level of glutamate was most likely at high toxic levels.

Answered 9/9/2020

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