Question 1

rnp antibody, speckled pattern, titer of 1:320.  no symptoms or anything. high complement c3 & c4 levels. do i have an autoimmune disease?

Accepted Answer

Not necessarily: Do you have any symptoms? If you do not, stay in touch with your doctor for follow-up care. An abnormal lab results does not make it auto-immune disease, but it does put you at a greater risk.
Avoid exposure to sun.

Question 2

my c4 complement level is low and c3 complement is at the low end of the range (90, ref range 90-180). what could this mean?

Accepted Answer

May be significant : Low Complement levels may be nonspecific markers for autoimmune disorders. Other symptoms and clinical findings are needed to be able to adequately answer your question.

Question 3

what do you think it means when your complement level comes back high (176) but you test a "low" postive for lupus? this is for my 18 month old son.

Accepted Answer

Need more: A diagnosis of lupus requires way more testing than this.

Question 4

i have normal levels of complement c2 and c4.  c3 level is low.  ch50 is high-normal(57 u/ml)-(all are serum tests)-what are the possible causes?

Accepted Answer

Labwork: Proper medicine would be not to treat lab values but the patient. Based on the lab values you provided it is impossible to suggest any kind of diagnosis. We would need to know your presentation and other labwork that was done in order to help you sort it out.

Question 5

could my severe vitamin d deficiency be the cause of my extremely high complement ch50 level?  c3 and c4 are normal.

Accepted Answer

No: I'd ignore the high ch50 levels. This is a lab test that's hard to do and even harder to interpret.

Question 6

what illness could explain elevated c3 and c4 complement serum levels in the presence of angioedema? ana and rheum arth factor both negative.

Accepted Answer

See details: Elevated levels mean nothing. The test were done to see in the C4 level was low and therefore would suggest hereditary angioedema..

Question 7

is a consistantly low c4 complement level but normal c1 inhibitor and functional level  normal for  hae if not in a flare?

Accepted Answer

Low C4: Yes this is normal for some hae patients, a low C4 is a hallmark of hae and you can have normal levels and function of c1 esterase inhibitor in between attacks in some individuals.

Question 8

what does a high complement 3 (c3) blood test result mean?

Accepted Answer

What are other: Findings. C3 is an acute phase reactant and will increase in many situations associated with inflammation. It would be usual to see isolated increase in c3.

Question 9

ana 1:1280 nucleolar and complement c3 high. what does this mean?

Accepted Answer

Maybe nothing: High complement is  not a problem. The problem is more  why do you have a + ana. The nucleolar pattern needs to be interpreted  with the clinical picture. Your evaluation will help clarify this. It may be germane to a helpth problem but i often see this wihtout an issue. This depends on the qulaity of the lab and what your clincial issues are.

Question 10

what does ana 1:1280 nucleolar and complement c3 high at 166 mean?

Accepted Answer

High C3 - nothing: High C3 means nothing.  ANA with nucleolar pattern could be related to scleroderma, but rheumatologic evaluation should clarify.

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Doctor answers about:

High c3 complement level

A member asked:

Rnp antibody, speckled pattern, titer of 1:320. no symptoms or anything. high complement c3 & c4 levels. do i have an autoimmune disease?

A member asked:

My c4 complement level is low and c3 complement is at the low end of the range (90, ref range 90-180). what could this mean?

A member asked:

What do you think it means when your complement level comes back high (176) but you test a "low" postive for lupus? this is for my 18 month old son.

A member asked:

I have normal levels of complement c2 and c4. c3 level is low. ch50 is high-normal(57 u/ml)-(all are serum tests)-what are the possible causes?

A member asked:

Could my severe vitamin d deficiency be the cause of my extremely high complement ch50 level? c3 and c4 are normal.

A member asked:

What illness could explain elevated c3 and c4 complement serum levels in the presence of angioedema? ana and rheum arth factor both negative.

A member asked:

Is a consistantly low c4 complement level but normal c1 inhibitor and functional level normal for hae if not in a flare?

A member asked:

What does a high complement 3 (c3) blood test result mean?

A member asked:

Ana 1:1280 nucleolar and complement c3 high. what does this mean?

A member asked:

What does ana 1:1280 nucleolar and complement c3 high at 166 mean?

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