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A member asked:
Is a consistantly low c4 complement level but normal c1 inhibitor and functional level normal for hae if not in a flare?
4 doctors weighed in across 2 answers
Low C4: Yes this is normal for some hae patients, a low C4 is a hallmark of hae and you can have normal levels and function of c1 esterase inhibitor in between attacks in some individuals.
Answered 2/13/2015
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Yes: The C4 and c1inh level are usually low even in the absence of an exacerbation.
Answered 2/13/2015
4.9k views
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Complement C3 & C4 tests done 3 times. C3 normal but twice C4 was borderline normal or borderline low, 3rd time it was well within range. deficiency?
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