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Cymbalta and wellbutrin together

A 45-year-old female asked:
Dr. Pamela Pappas
Psychiatry 42 years experience
Interaction: Although these 2 can be used together safely, caution is needed with the doses. Wellbutrin can inhibit the metabolism of cymbalta, (duloxetine) causi... Read More
Dr. Raju Indukuri
Psychiatry 45 years experience
Comb meds: Wellbutrin xl 300 mg and may be 30 mg Cymbalta (duloxetine) are safe. There is no 40 mg cymbalta (duloxetine). Even a 60 mg Cymbalta (duloxetine) ... Read More

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A 47-year-old female asked:
Dr. Cyma Khalily
Psychiatry 35 years experience
YES!!!: Yes this is a very potent combination and excellent synergy. Cymbalta (duloxetine) helps with serotonin and norepinephrine and wellbutrin helps with D... Read More
A 45-year-old female asked:
Dr. Raju Indukuri
Psychiatry 45 years experience
Too much medicine: You may experience jitteriness or increase anxitey due to excessive nor epinephrine.
Dr. Donald Jacobson
A Verified Doctoranswered
A US doctor answeredLearn more
Toxicity: Wellbutrin (bupropion) toxicity drowsiness tremor extrapyramidal symptoms hallucinations convulsions loss of consciousness respiratory de... Read More
A 48-year-old member asked:
Dr. Omar Reda
Psychiatry 25 years experience
Yes: Cymbalta (duloxetine) and Wellbutrin are potent anti-depressants. They are not usually prescribed together unless it is a severe case of depression. A... Read More
A 38-year-old male asked:
Dr. Melissa Haglund
Internal Medicine 23 years experience
Depends: If anxiety is a consideration, Cymbalta (duloxetine) is better as Wellbutrin does not address anxiety and can make it worse. Both are fine to take wit... Read More
A 35-year-old member asked:
Dr. Alan Ali
Dr. Alan Alianswered
Psychiatry 32 years experience
Withdrawal Cymbalta (duloxetine): Establish a slow tapering plan with the help from your prescribing md.
A 51-year-old female asked:
Dr. Heidi Fowler
Psychiatry 25 years experience
If you are having: thoughts about killing yourself, get seen at the nearest emergency room now. Have a friend or relative drive you or call 911 for emergency services f... Read More
A member asked:
Dr. John Baker
Neurology 14 years experience
Glaucoma: There is caution recommended for Cymbalta (duloxetine) in people with 'uncontrolled' angle closure glaucoma, not open angle glaucoma. Wellbutrin is no... Read More
A 48-year-old male asked:
Dr. Lynne Weixel
Clinical Psychology 36 years experience
Risky side effects: The combination can raise the risk of side effects including seizures. It's not a good idea unless absolutely necessary and will be closely watched. D... Read More
A 44-year-old female asked:
Dr. Lawrence Dunn
Psychiatry 37 years experience
Cymbalta Wellbutrin: Cymbalta and Wellbutrin can be safely combined. The Cymbalta levels may be increased, but I have not seen this become a problem. The addition of Wellb... Read More

90,000 U.S. doctors in 147 specialties are here to answer your questions or offer you advice, prescriptions, and more. Get help now:

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