Question 1

i had an ana ifa screen w/reflex to titer and pattern blood test & the results were a homogeneous pattern is associated with systemic lupus erythematosus, drug-induced lupus. is there a way to prove it is not drug-induced lupus? i take no medications?

Accepted Answer

: Anti histone antibody is classically associated with drug induced lupus.  Another question would be - what are the signs and symptoms suggesting lupus?  Most ANA are not significant.  Figures from 5-10% of the general population show positive lupus testing.  Most will never go on to lupus, fortunately.

Question 2

random all over body tingling- positive ana ifa screen, ana titer speckled 80, elevated bun and bun/crea, elevated rdw-sd. just trying to figure out what it might be pointing to. thanks!?

Accepted Answer

: Your symptom is quite nonspecific and I do not think there is any relationship with your blood test results. ANA titer 80 with speckled pattern does not have any diagnostic value and those abnormalities (high BUN, high BUN/Creat and high RDW) need to be interpreted individually, they are not typical manifestations of a certain problem.

Question 3

ana ifa screen test= results were ana screen, ifa positive & ana titer 1:160 & screening detecting the presence of 150 autoantibodies in various autoimmune diseases, ana patterns (roq)= normal, would it be systemic lupus or drug-induced lupus?

Accepted Answer

: Autoimmune conditions are not diagnosed on labs alone. The whole clinical picture must be taken into account. It is not unusual to have a positive ANA and no defined autoimmune illness. You need to follow up with the doctor who ordered your tests for next steps.

Question 4

positive ana ifa screen with reflex is it contagious?

Accepted Answer

No: This isn't a screen for an infectious disease, and many people have a positive ANA yet are perfectly healthy -- in fact, there are probably more people in whom it's a non-finding than who have ANA-associated illness.

Question 5

what is the definition or description of: ana ifa screen?

Accepted Answer

A lab test.: Anti-nuclear antibodies (anas) are autoantibodies directed against certain parts of a cell nucleus. Anas are present in increased amounts in a variety of  autoimmune diseases. An ANA test measures the pattern and amount of these autoantibodies that can attack the body's tissues as if they were foreign. An indirect fluorescent antibody (ifa) test is one that uses two antibodies for detection.

Question 6

ana titer with reflex to ifa of 1:320 and neg for antibody tests what does that mean? pattern was speckled and homogeneos

Accepted Answer

See details: You have a positive ANA which is a screening test for lupus. However, it is positive in numerous other diseases and even in normal people. See a rheumatologist to determine what it means.

Question 7

how about ana screen positive, ana titer (ifa) 1:80 hi, and pattern speckled?

Accepted Answer

How about it?: Up to a quarter of women your age have an ANA (immunofluorescent antibody) at a low titer like yours with a speckled pattern. If there's a question of whether you have lupus or one of its relatives, it's a piece of information to note and file for future reference. A negative ANA would rule several things out.  Your result proves nothing positive. Best wishes.

Question 8

i recieved a positive ana screen,ifa with a ana titer of 1:40 h and nucleur, speckled ana pattern. i've been researching this all day and cannot calm down my anxiety and worry . is this something to be worried about?

Accepted Answer

: Yes, this is considered a positive result &amp; a speckled nuclear pattern can be seen in various disorders. You don't describe your symptoms. The combination of ANA testing and characteristic symptoms are required in order to diagnose autoimmune disease. A rheumatologist is best qualified to evaluate,advise,treat &amp; follow you. Further appropriate testing will be ordered,I'm sure.

Question 9

i had blood work done, and tested positive on the ana screen ifa w/ refl titer and pattern. with nuclear, dense fine speckled pattern. ana titer 1:320 h . no follow up until the 12th , and i'm panicking. seeing lupus on google ??

Accepted Answer

: Positive ANA with 1:320 titer is truly positive but it does not mean you have lupus, especially with that pattern. You should let us know the reason why you had this serology test done. Do not panic, ANA antibody is not specific to any specific auto-immune disease, just follow up with your doctor for further information.

Question 10

what could a positive ana screen, ifa, w/refl titer and pattern (only 1:40) which is nuclear, homogeneous s, mitotic intercellular bridge mean? say that 3 times quickly. curious before dr appointment. on humira 3 months for axspa. ty?

Accepted Answer

: All laboratory results need to be interpreted in the clinical context and the doctor who ordered the tests is usually in the best position to do that. Talk to the doctor who ordered the tests. Having said that, it appears that you have an auto-immune disorder for which you are taking Humira. If that is the case a positive ANA at 1:40 is not meaningful.    
Wish you good health!

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Doctor answers about:

Ana ifa screen with reflex to titer

A member asked:

I had an ana ifa screen w/reflex to titer and pattern blood test & the results were a homogeneous pattern is associated with systemic lupus erythematosus, drug-induced lupus. is there a way to prove it is not drug-induced lupus? i take no medications?

A member asked:

Random all over body tingling- positive ana ifa screen, ana titer speckled 80, elevated bun and bun/crea, elevated rdw-sd. just trying to figure out what it might be pointing to. thanks!?

A member asked:

Ana ifa screen test= results were ana screen, ifa positive & ana titer 1:160 & screening detecting the presence of 150 autoantibodies in various autoimmune diseases, ana patterns (roq)= normal, would it be systemic lupus or drug-induced lupus?

A member asked:

Positive ana ifa screen with reflex is it contagious?

A member asked:

What is the definition or description of: ana ifa screen?

A member asked:

Ana titer with reflex to ifa of 1:320 and neg for antibody tests what does that mean? pattern was speckled and homogeneos

A member asked:

How about ana screen positive, ana titer (ifa) 1:80 hi, and pattern speckled?

A member asked:

I recieved a positive ana screen,ifa with a ana titer of 1:40 h and nucleur, speckled ana pattern. i've been researching this all day and cannot calm down my anxiety and worry . is this something to be worried about?

A member asked:

I had blood work done, and tested positive on the ana screen ifa w/ refl titer and pattern. with nuclear, dense fine speckled pattern. ana titer 1:320 h . no follow up until the 12th , and i'm panicking. seeing lupus on google ??

A member asked:

What could a positive ana screen, ifa, w/refl titer and pattern (only 1:40) which is nuclear, homogeneous s, mitotic intercellular bridge mean? say that 3 times quickly. curious before dr appointment. on humira 3 months for axspa. ty?

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