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Mast cell

Mast cell

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Innate immune cell prevalent in tissue and surrounding small blood vessels. Acts as a source of histamine and other rapid acting mediators of an inflammatory response to tissue infection or damage. Inappropriate activation of mast cells is central to many allergy-related diseases including anaphylaxis. Inappropriate population expansion or activity results in mast cell activation disorders

Dr. Corey Clay reviewed this

12 year experience in Allergy and Immunology

How long it usually lasts:

Chronic (lasts years to lifelong)

Related questions

A 58-year old female asked:

What is nonclonal mast cell activation disorder?

1 doctor answer • 2 doctors weighed in

A 40-year old female asked:

Is there any medications for mast cell activation ?

1 doctor answer • 2 doctors weighed in

A 28-year old male asked:

What is the definition or description of: mast cell?

2 doctor answers • 2 doctors weighed in

A 33-year old asked:

What binds to mast cells and causes them to degranulate?

1 doctor answer • 2 doctors weighed in

A 41-year old female asked:

What can you tell me about the diagnosis of Mast Cell Activation Syndrome?

2 doctor answers • 4 doctors weighed in

A 38-year old asked:

Are mast cell tumors people tumors or dog tumors?

1 doctor answer • 1 doctor weighed in

A 32-year old female asked:

My CU index was 35. My histamine releasing was normal. Does this mean I have Mast Cell??

1 doctor answer • 1 doctor weighed in

A female asked:

Can multiple foods intolerance developed within months in a teen girl with celiac be a sign of mast cell activation disorder?

1 doctor answer • 1 doctor weighed in

A 57-year old female asked:

Is it possible to have mast cell activation syndrome with normal tryptase levels? If so, how can the dr be sure you really have it

1 doctor answer • 1 doctor weighed in

A 22-year old female asked:

What are mast cells in nostrils is that a tumor?

1 doctor answer • 1 doctor weighed in

A 57-year old female asked:

How is mast cell dysfunction different than an allergy?

3 doctor answers • 6 doctors weighed in

A 57-year old female asked:

What does a mast cell activation disorder rash look like?

1 doctor answer • 2 doctors weighed in

A 59-year old female asked:

What is mast cell disease and how does it manifest in infants?

1 doctor answer • 2 doctors weighed in

A 29-year old asked:

What are some problems for an infant born with an overadundance of mast cells?

1 doctor answer • 1 doctor weighed in

A 57-year old female asked:

What is the difference between mast cell activation syndrome and mastocytosis?

2 doctor answers • 3 doctors weighed in

A 57-year old female asked:

Is there any connection between mast cell activation/connective tissue problems and sacroiliitis?

1 doctor answer • 2 doctors weighed in

A 36-year old female asked:

What kind of test is E893 Mast cell Tryptase for 5 year old...what are they looking for...thanx?

2 doctor answers • 3 doctors weighed in

A member asked:

Can you have MCAS (Mast Cell Activation Syndrome) without an elevated tryptase level, even while symptomatic?

1 doctor answer • 1 doctor weighed in

A 32-year old female asked:

What would you find on biopsy (from scopes) in mastocytic enterocolitis? Other than the mast cells. Thank you.

1 doctor answer • 1 doctor weighed in

A 57-year old female asked:

Mastocytosis has specific diagnostic criterion. Does mast cell activation syndrome have specific criterion? If so, what is the criterion?

3 doctor answers • 3 doctors weighed in

A 49-year old female asked:

Was taking provigil but can't take anymore because I have mast cell and it releases histamine. What could take that don't release histamine ?

1 doctor answer • 2 doctors weighed in

A 22-year old female asked:

If the patient(The patient already has sensitized to mast cells by having sea foods and shows allergic response) will have the same sea food in future or will not the patient eat the same food again?

1 doctor answer • 1 doctor weighed in

A 25-year old female asked:

What would cause mast cells to be in the biopsy of my duodenum?

1 doctor answer • 2 doctors weighed in

A 36-year old female asked:

Can h pylori cause mast cell activation disease?

1 doctor answer • 1 doctor weighed in

A 48-year old asked:

What is the difference between an abscess and a mast cell tumor?

2 doctor answers • 4 doctors weighed in

A 57-year old female asked:

Is there any relationship between a pterygium and mast cell activation syndrome?

1 doctor answer • 2 doctors weighed in

A 18-year old male asked:

Does desloratadine have a mast-cell stabilising effect which can cure an allergy?

1 doctor answer • 4 doctors weighed in

A 42-year old female asked:

What are the tests for diagnosing Mast Cell Activation Syndrome? And what kind of doctor do I need to go to?

2 doctor answers • 3 doctors weighed in

A 29-year old asked:

Is chronic urticaria a mast cell disease?

3 doctor answers • 14 doctors weighed in

A 39-year old asked:

Whats chronic urticaria vs mast cell disease?

1 doctor answer • 2 doctors weighed in

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