A member asked:

How is mast cell dysfunction different than an allergy?

6 doctors weighed in across 3 answers
Dr. Joseph Mele answered

Specializes in Plastic Surgery

Mast Cells: Mast cells are an important part of the immune system. They are involved in allergies, anaphylaxis, wound healing and defense. In allergies, they are functioning normally, but excessively. Dysfunction implies they are not acting normally.

Answered 9/25/2013

4.9k views

Thank

They are similar : Mast cell disease is an over production of mast cells which release substances that cause allergy like symptoms. Allergies are your normal cells recognizing pollen, foods, medicines, or venom as foreign and reacting to them. Avoiding the triggers is most important. Then you can treat with medicines.

Answered 9/17/2013

4.9k views

Thank

Mast cells: Mast cells are at the base of allergic disorders but when they dysfunction, that means they are firing in all directions and can causes systemic symptoms beyond allergies and asthma. They can cause cardiac problems and anaphylaxis. They may turn malignant in a small percentage of people also. Mast cell dysfunction can be a prerequisite for mastocytosis.

Answered 10/8/2017

4.9k views

Thank

Related Questions

A member asked:

Can milk allergy cause high white blood cell count?

A doctor has provided 1 answer