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Can you have MCAS (Mast Cell Activation Syndrome) without an elevated tryptase level, even while symptomatic?
Ive been having chronic hives since April. My IGe was 154 should be under 25 and my histamine release test was over 50 and it should be under 10. My tryptase was normal- do you think I may have mast cell activation?
40Y/O F.Bone mrw bx shows no cancer, only small cluster of mast cells, they are spindled and express cd25.Serum tryptase level is normal.No ckit mutation.Had bx bc of chronic lymphocytosis.Been followed over 1 yr,blood stays the same. What cld it be?
40yo/F.Rec labs uploaded.chronic lymphocytosis.Had bone marrow biopsy checking for cancer,only found small cluster of mast cells, show cd25 and spindled.But NO cKit mutation and normal tryptase levels.Blood stays about the same?Been followed over 1yr?
Curious if there's other reasons besides mastocytosis that gi biopsies would be tryptase/cd117/cd25 +? Those mast cells appeared normal & serum tryptase is only high normal at baseline. Tests done bc of frequent gi issues, anaphylaxis etc. Thanks?
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