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A 24-year-old female asked:

What does it mean when a pap comes back saying cellular changes associated with inflammation are present ? chlamydia, gon & hpv negative.

2 doctor answers2 doctors weighed in
Dr. Hunter Handsfield
Infectious Disease 55 years experience
Pap inflammation: Pap smears often show inflammation. The cause usually isn't clear -- little research has been done. However, STDs probably are rare. For sure it's not HPV, which doesn't cause inflammation. If you're at risk for STD, you need testing for gonorrhea and chlamydia; the pap smear doesn't help diagnose them at all.
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Dr. Gurmukh Singh
Pathology 51 years experience
Agree with Dr. H: Follow your doctor's advise regarding repeat PAP tests at intervals recommended by your doctor. Get HPV vaccine. Have a healthy diet, exercise 30 minutes/day, drink plenty of water, have safe sex, no tobacco alcohol weed or street drugs. For nutrition: http://www.choosemyplate.gov/. Wish you good health!
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Related questions

A 37-year-old female asked:
Pap smear result shows reactive cellular changes. Does this indicate hpv? Also shows moderate inflammation.Followup recommended. What does this mean
Dr. Ed Friedlander
Pathology 46 years experience
It does not: You have some inflammation due perhaps to mild physical injury or a non-hpv infection. The smear should probably be repeated because the injury change... Read More
Created for people with ongoing healthcare needs but benefits everyone.
A 36-year-old female asked:
Pap HPV negative & negative for intraepithelial lesions or malignancy but noted moderate inflammation. What does that mean? sex occurred 48hr before
Dr. Hunter Handsfield
Infectious Disease 55 years experience
Nonspecific finding: Inflammation on a pap smear is very nonspecific -- i.e. there are many potential causes. It's so common that many gyns don't even consider it abnormal... Read More
Created for people with ongoing healthcare needs but benefits everyone.
A 23-year-old female asked:
Ayear back and my pap smear report same back as LSIL. This year, the repeat pap came back as Negative for NILM but inflammatory smear. Is the only cause for LSIL HPV? Could it be cause by inflammation or pcos too? Should I be worried ab high risk hpv?
Dr. Hunter Handsfield
Infectious Disease 55 years experience
HPV is the only known cause of LSIL, but usually with low risk types of the virus. Inflammatory changes on Pap sometime are due to other infections (e... Read More
Created for people with ongoing healthcare needs but benefits everyone.
View all answers
A 29-year-old female asked:
I had a slightly abnormal pap with negative on HPV and all STDs. My gyno said it could be inflammation due to sex. Is this true? What else could it be
Dr. Addagada Rao
General Surgery 58 years experience
Follow through: by frequent scheduled visits to your gyn doctor for PAP and HPV monitoring. Normal physiological acts ( sex ) should not produce abnormal reaction(s)... Read More
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A female asked:
Pap/ HPV reflex to hpv16/18 with ct/cg show endocervical , glandular or metaplastic cells/ or parabasal cells present. Is this simply inflammation?
Dr. Douglas Miller
Pathology 43 years experience
Not clear: I'm not clear on your question. If your pap smear identified hpv types 16 and 18, then you are infected with these "high risk" subtypes of human papi... Read More
Created for people with ongoing healthcare needs but benefits everyone.
Last updated Feb 9, 2020

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