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A 34-year-old male asked:

I had syphilis in 2014. the rpr was 1:128. got 3 penicilin shots. my most recent blood test shows rpr 1:4. does that mean i got reinfected?

1 doctor answer2 doctors weighed in
Dr. Hunter Handsfield
Infectious Disease 54 years experience
Probably not: Successful cure is defined by a 3-dilution decline in RPR or VDRL titer. Your decline is 5 diultions, so probably all is well. However, if your titer previously declined to a lower level, i.e. negative or under 1:4 and now has risen to 1:4, reinfection is possible. Best to discuss with the doctor or clinic where you were treated, but most likely no problem.
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Last updated Jul 9, 2019


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