Palm Beach, FL
A 55-year-old male asked:

What is the exact formula for calculating free testosterone based on total testosterone, albumin and sex hormone binding globulin?

1 doctor answer2 doctors weighed in
Dr. Alvin Lin
Geriatrics 32 years experience
Several available: Check out http://www.Issam.Ch/freetesto.Htm for a free testosterone calculator available online. Check out http://www.Eje-online.Org/content/152/3/471.Full for study regarding accuracy of several other calculators.
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Dr. Alvin Lin
Dr. Alvin Lin commented
Geriatrics 32 years experience
Provided original answer
"But what is the formula used on line? Can I calculate it myself?" Click on 1st hyperlink above, then "Explanation and examples" hyperlink to find formula.
Oct 1, 2012

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A 55-year-old male asked:
What is the formula for calculating free testosterone from total t, shbg and albumin? I don't want the online calculator, I want to crunch the numbers
Dr. Ed Friedlander
Pathology 46 years experience
Good for you!: The free androgen index is the total testosterone divided by the steroid hormone binding globulin, as a percent (multiply by 100). Be sure you have th... Read More
Created for people with ongoing healthcare needs but benefits everyone.
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A 64-year-old male asked:
Total testosterone is 1, 146, shbg is 99, albumin is 5.0. Quest calcs free t as 61.7 pg/ml. Online research-based calcs free t as 119.0. Which correct?
Dr. James Lin
A Verified Doctoranswered
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Okay..., but...: As a clinician, i interpret the report of testosterone in conjunction with patient's overall manhood, mentally and physically, and don't do it by numb... Read More
Created for people with ongoing healthcare needs but benefits everyone.
A 64-year-old male asked:
Test results: total testosterone = 1, 146 ng/dl, shbg = 99nmol/l, albumin = 5.0 g/dl, free t = 61.7 pg/ml. Free t calculation seems too low. Help?!
Dr. Lisa Hogan
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Convert units: The number will make more sense if you convert pg/ml to ng/dl (which is how the total testosterone value is given). This is easy; just multiply by 10... Read More
Created for people with ongoing healthcare needs but benefits everyone.
A 31-year-old male asked:
Testing for AL amyloid. SPEP shows no M-spike but mildly elevated total protein & A/G ratio (2.7) due to high albumin. Globulins well within normal range. Worrisome? Serum/urine IFE &marrow biopsy ok, but elevated free K/L ratio due to low lambda.
Dr. Ed Friedlander
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Stop worrying: High albumin simply means either that you were a bit dehydrated / thirsty or that you're one of the few % who naturally fall outside the reference ran... Read More
Created for people with ongoing healthcare needs but benefits everyone.
Dr. Ed Friedlander
Pathology 46 years experience
Provided original answer
THanks for the follow-up and for your kind words. Best wishes.
Nov 1, 2016
Dr. Gurmukh Singh
Pathology 51 years experience
Agree with Dr. Friedlander. The only thing I would add is that K/L ratio is a useless test.
Nov 2, 2016
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A 33-year-old male asked:
Metabolic panel total protein 8.3. Albumin 4.7 and globulins 3.6 with all other values mid range and negative hepatitis panel and 4th gen hiv test negative 6 months from sex do those results sound high? Dr said no cause for concern but Im concerned?
Dr. Donald Colantino
Internal Medicine 63 years experience
I agree with your physician that these borderline high values are no cause for concern. If you still have concerns you can have a serum electrophores... Read More
Created for people with ongoing healthcare needs but benefits everyone.
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Last updated Feb 4, 2019

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