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A 33-year-old member asked:

Test for syphilis - what do rpr reac and vdrl reac mean?

2 doctor answers5 doctors weighed in
Dr. Joseph Woods
Pathology 30 years experience
Screening tests.: Vdrl (venerial disease research laboratory) tests against anti-cardiolipin antibodies and RPR (papid plasma reagin) tests against nonspecific antibodies suggestive of syphilis and are screening tests. Treponemal antibody tests, like fta-abs and mha-tp usually become positive two to five weeks after the initial infection. These are used to confirm syphilis and stay positive, even after therapy.
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Dr. Ed Friedlander
Pathology 46 years experience
Positive tests: You may want to follow them up with more specific tests, or your physician may simply treat depending on history.
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Related questions

A 30-year-old male asked:
Rash on palm and feet 1month not itchy or hurt ,air-fill blister 1st week of rash test HIV rapid , syphilis TPHA , VDRL/RPR all is negative 3rd week re-test again still negative Dr doxycycline100mg x2/d for 2 week do i was treat correctly?
Dr. Hunter Handsfield
Infectious Disease 55 years experience
Not HIV or syphilis: With these test results plus continuing rash afer 2 weeks of doxycycline, you can be 100% certain neither HIV nor syphilis is the cause of the rash o... Read More
Created for people with ongoing healthcare needs but benefits everyone.
A 30-year-old male asked:
I had rapid syphilis test at week 5, RPR at week 8, rapid syph 13 week, VDRL&TPHA 16week after exposure all negative, but i have rash on hand and feet, also i consume azithromycin 500mg x 2pills at week 3, am i need retest for syphilis at week 24?
Dr. Jay Park
Dr. Jay Parkanswered
Pediatrics 52 years experience
Negative VDRL & TPHA tests at 16 weeks post exposure assure you that you were not infected.
Created for people with ongoing healthcare needs but benefits everyone.
Dr. Hunter Handsfield
Infectious Disease 55 years experience
Stop testing. You do not have syphilis and never did.
Sep 16, 2022
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A 28-year-old male asked:
What is the definition or description of: vdrl/rpr positive for syphilis?
Dr. Dominic Riganotti
Infectious Disease 27 years experience
Antibodies: Ok..Lets separate these first. The venereal disease research laboratory test or vdrl is a blood test for syphilis and was developed by the former vene... Read More
Created for people with ongoing healthcare needs but benefits everyone.
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A 30-year-old male asked:
Is a negative tpha 3months & rapid syphilis tpha 6months after exposure enough to exclude syphilis even i experience some symptoms like rash on soles, extreme hair lose,fatigue? or i need do a vdrl/rpr?
Dr. Birendra Tandan
Urology 36 years experience
Yes it should be. Just stay under care of your doc.
Created for people with ongoing healthcare needs but benefits everyone.
A 27-year-old male asked:
Vdrl (rpr) conclusive at 60 days post exposure? which involved handjob and breast sex(protected). No concerns for hiv but syphilis. had a little open sore on left knee after 3 weeks and painless rash on right knee aftr 5 weeks,gone in 5 days TYSM?
Dr. Gurmukh Singh
Pathology 51 years experience
Visit this site for information on this topic: Syphilis window period: https://www.e7health.com/post/155/std-test-window-when-should-i-get-tested/#:~:... Read More
Created for people with ongoing healthcare needs but benefits everyone.
Last updated Jan 12, 2015

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