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Farmingdale, NY
A 50-year-old female asked:

Can someone with genital herpes have a western blot when there's no outbreak?ive had hsv1 on mouth many times,blood test said hsv2 1.25 & hsv1 5.0

2 doctor answers3 doctors weighed in
Dr. Ed Friedlander
Pathology 44 years experience
Of course: These serologic tests tell you nothing about whether you ever have outbreaks. Many of us question their value except in confirming clinical suspicion of active or episodic infection.
Dr. Claude Parola
Internal Medicine 40 years experience
HSV western blot: A western blot is perform to confirm an ELISA positive test ( antibody detection). When an antibody is detected , it doesn't tell 100% of the time if it is because of HSV or from any other virus, so to determine if it is due to HSV for example, certain protein from a known sample of HSV is made to react with the antibody detected to see if it is from HSV or not, active infection isn't necessary

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Last updated Sep 29, 2016

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