A member asked:

Can someone with genital herpes have a western blot when there's no outbreak?ive had hsv1 on mouth many times,blood test said hsv2 1.25 & hsv1 5.0

3 doctors weighed in across 2 answers
Dr. Ed Friedlander answered

Specializes in Pathology

Of course: These serologic tests tell you nothing about whether you ever have outbreaks. Many of us question their value except in confirming clinical suspicion of active or episodic infection.

Answered 2/6/2015

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Dr. Claude Parola answered

Specializes in Internal Medicine

HSV western blot: A western blot is perform to confirm an ELISA positive test ( antibody detection). When an antibody is detected , it doesn't tell 100% of the time if it is because of HSV or from any other virus, so to determine if it is due to HSV for example, certain protein from a known sample of HSV is made to react with the antibody detected to see if it is from HSV or not, active infection isn't necessary

Answered 9/29/2016

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