Yonkers, NY
A 26-year-old female asked:
i have an anal fissure and was prescribed a nifedipine ointment. will using more often/more than a pea-sized drop do me harm?
3 doctor answers • 6 doctors weighed in
Dr. James Ferguson answered
Pediatrics 46 years experience
Maybe,maybe not : The dose you listed is considered more than adequate for the medication to work. Both 2 and 3 x daily dosing has been suggested in references. A variety of side effects including dizziness, nausea, light headedness, pallor and heart rate changes are occasionally seen and may be more likely with a larger dose.Larger doses will not necessarily speed healing.
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Dr. Robert Grieco answered
Family Medicine 37 years experience
No: The nifepinine works by relaxing the rectal muscles. There is a limited rate that it can diffuse through the rectal lining into the muscles. Putting more cream on may not increase how well it works but shouldn't harm you. Realize that it is not a pain reliever or an anti-infamitory so relief will take time. Don't over do it because that just irritate things. Good health.
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Dr. Diane Minich answered
Family Medicine 37 years experience
Use as directed: Use medications as directed only. Do not use more than directed by your doctor.
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1 comment
Dr. Vicki Levine commented
Dermatology 41 years experience
probably not but I do not recommend you doing this on a regular basis since you're using it on a mucosal surface it is more easily absorbed that if you were just putting it on your skin
Mar 9, 2014
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Last updated Nov 16, 2015
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