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San Antonio, TX
A 45-year-old female asked:

Is it possible to become resistant to valtrex (valacyclovir) and it stops working as well as before?

1 doctor answer3 doctors weighed in
Dr. Joel Gallant
Infectious Disease 36 years experience
Yes, but rare: It's possible but very unusual. It tends to happen only in immunosuppressed patients who have taken intermittent Acyclovir or valacyclovir for many years. If you develop a herpes lesion while taking valtrex, the lesion can be cultured and sent to the lab for sensitivity testing, which will determine whether the herpes is sensitive or resistant.

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Last updated Sep 28, 2016

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