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San Antonio, TX
A 45-year-old female asked:

Is it possible to become resistant to valtrex (valacyclovir) and it stops working as well as before?

1 doctor answer4 doctors weighed in
Dr. Joel Gallant
Infectious Disease 38 years experience
Yes, but rare: It's possible but very unusual. It tends to happen only in immunosuppressed patients who have taken intermittent Acyclovir or valacyclovir for many years. If you develop a herpes lesion while taking valtrex, the lesion can be cultured and sent to the lab for sensitivity testing, which will determine whether the herpes is sensitive or resistant.
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Related questions

A 26-year-old female asked:
Everytime I have sex my symptoms act up and it is painful and sore so I stop and double my Valtrex (valacyclovir) then have sex and it happens again- advice?
Dr. Hunter Handsfield
Infectious Disease 55 years experience
Not herpes: Sex doesn't trigger herpes outbreaks. Something else probably is causing these symptoms, especially if you only have vaginal irritation without visibl... Read More
Created for people with ongoing healthcare needs but benefits everyone.
A 23-year-old female asked:
My doctor has me on a Valtrex (valacyclovir) treatment 1 pill every 12 hours for the coldsores on my lips. If i stop the pills will the coldsores appear right away?
Dr. Collin Smikle
Obstetrics & Gynecology 38 years experience
Cold sores: The cold sores are caused by one of the herpes viruses, either type i or type ii. The second was considered just genital but you can be infected in a... Read More
Created for people with ongoing healthcare needs but benefits everyone.
A 40-year-old male asked:
Im taking Valtrex (valacyclovir) on a daily basis, plus super lysine 1500mg, and vitamins c and zinc. Yet i continue to have outbreaks that lasts for a week or two. I watch what i eat, stop smoking! please help me!
Dr. LUIS IRIZARRY
A Verified Doctoranswered
30 years experience
HSV 2: Make sure the dose of Valtrex (valacyclovir) is about 500-1, 000mg daily. Have your doctor do blood tests to check you immune status. Stress, anxiety ... Read More
Created for people with ongoing healthcare needs but benefits everyone.
View all answers
A 22-year-old female asked:
I have hsv2. I lay in bed with fever and body aches 2-3 days a month. Valtrex (valacyclovir) makes my hair fall out. I feel like death. Will these experiences stop?
Dr. Hunter Handsfield
Infectious Disease 55 years experience
Probably not herpes: Sorry to hear how tough this has been. But I doubt herpes is really the problem. I'm not doubting you have HSV2, but it does not cause fever and body ... Read More
Created for people with ongoing healthcare needs but benefits everyone.
A 40-year-old male asked:
Would generic Valtrex (valacyclovir) be as good as the real thing?
Dr. Chevies Newman
Obstetrics and Gynecology 24 years experience
Yes: Generics have to be very similar to the original to be sold as such and it saves u dough.
Created for people with ongoing healthcare needs but benefits everyone.
Last updated Dec 29, 2022

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