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A member asked:
Had a colonoscopy and the biopsies showed a change is the cell type, called interstinal metaplasia. what does that mean?
3 doctors weighed in across 2 answers
Need follow up: Metaplasia means area of biopsy , did not have normal looking mucosa , cells are changing , it does not mean cancer , still cell are normal cells , if unchecked theses areas may transform to malignant cells , if cluster of cancer cells are formed , if they are not invading to adjacent membrane is called ' in situ cancer ' earliest possible stage .Do not worry just follow your doctors advise , .
Answered 9/28/2016
4.9k views
Transformation to Ca: Cancers do not start denovo as a malignant lesion. In the bowel where bx can detect early transformation one sees a variety of pathologic changes. In about 10% of cases an adenomatous polyp is found. In 90% of changes there is a field effect with normal cells producing tumor protein. This moves on to atypical appearing cells dysplasia and then the early malignant lesion . Follow with bx.
Answered 7/3/2015
2.6k views
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