A 26-year-old female asked about a 58-year-old female:
Gallbladder cancer with severe lung metastasis 4th stage, does chemotherapy work?
2 doctor answers • 7 doctors weighed in

Dr. Andrew Turrisianswered
Radiation Oncology 49 years experience
GB cancer is: Uncommon, so few studies done prospectively. Looking at results in people treated empirically, perhaps one person in 10 will respond. That needs to be balanced against side effects that tend to occur in most. Frank discussion about symptom rrelief focus rather than "shrink tumor" at all cost.
Created for people with ongoing healthcare needs but benefits everyone.
4.9k viewsReviewed >2 years ago

Dr. Sewa Legha commented
Medical Oncology 52 years experience
There is one Prospective randomized trial(NEJM, April 2010) which showed significant improvement in Survival with a combination chemotherapy regimen of Gemcitabine+Cisplatin. It is an option which could be exercised.
Sep 22, 2013

Dr. Sewa Leghaanswered
Medical Oncology 52 years experience
It is worth a trial: Being a rare cancer, we have limited data about efficacy of chemotherapy. Yet many phase 2 studies have been done which predictably show that gemcitabine is an active drug and benefits about1/3 patients. More recently combination chemotherapy using Cisplatin with gemcitabine , for the first time, showed a superior efficacy with 2 drugs over one . You have nothing to lose yet may buy 6 to 12 months.
Created for people with ongoing healthcare needs but benefits everyone.
4.9k viewsReviewed >2 years ago
Last updated Jun 24, 2014
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