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A 26-year-old female asked about a 58-year-old female:

Gallbladder cancer with severe lung metastasis 4th stage, does chemotherapy work?

2 doctor answers7 doctors weighed in
Dr. Andrew Turrisi
Radiation Oncology 47 years experience
GB cancer is: Uncommon, so few studies done prospectively. Looking at results in people treated empirically, perhaps one person in 10 will respond. That needs to be balanced against side effects that tend to occur in most. Frank discussion about symptom rrelief focus rather than "shrink tumor" at all cost.
Dr. Sewa Legha
Dr. Sewa Legha commented
Medical Oncology 50 years experience
There is one Prospective randomized trial(NEJM, April 2010) which showed significant improvement in Survival with a combination chemotherapy regimen of Gemcitabine+Cisplatin. It is an option which could be exercised.
Sep 22, 2013
Dr. Sewa Legha
Medical Oncology 50 years experience
It is worth a trial: Being a rare cancer, we have limited data about efficacy of chemotherapy. Yet many phase 2 studies have been done which predictably show that gemcitabine is an active drug and benefits about1/3 patients. More recently combination chemotherapy using Cisplatin with gemcitabine , for the first time, showed a superior efficacy with 2 drugs over one . You have nothing to lose yet may buy 6 to 12 months.

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Last updated Jun 24, 2014

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