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A 29-year-old member asked:

can you still sickle cell if you're >3/4 white?

3 doctor answers5 doctors weighed in
Dr. David Escobar
Dr. David Escobar answered
Family Medicine 9 years experience
Yes: While sickle cell disease is most common in those of african, or african-american descent, one can still acquire the disease genetically based on their heredity.
Dr. Alan Ali
Dr. Alan Ali answered
Psychiatry 32 years experience
Sickle cell: Possible, need lab workup to confirm or rule our.
Dr. James Ferguson
Pediatrics 46 years experience
Yes: If you have true SS disease you inherit a defective sickle cell gene from both parents. That means they both carried one defective gene ( in a pair tasked with making proper hemoglobin). It doesn't matter how far back in their family tree it started, or that it ever showed up before.

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A 42-year-old member asked:

What is sickle cell disease?

4 doctor answers8 doctors weighed in
Dr. Richard Chudacoff
Obstetrics and Gynecology 32 years experience
Abnormal blood cells: Sickle cell disease occurs when there is an abnormal type of hemoglobin in blood cells. Thought to be a survivor advantage against malaria, when these cells have too little oxygen they collapse and get stuck in small vessels. This cuts off the blood supply to organs and causes severe pain. Sickle cell traits is when only half the genes code for the abnormal hemoglobin, usually not symptomatic.
A 52-year-old member asked:

Can you have partial sickle cell disease?

2 doctor answers5 doctors weighed in
Dr. Shabbir Hossain
Internal Medicine 16 years experience
Sickle cell trait: If you only have 1 of the two genes for sickle cell disease, you have sickle cell trait. This is a benign finding with no real symptoms. It's main significance is that you can pass this gene on to your children. If your partner also has sickle cell trait, then there is a probability that a child in the next gen will have sickle cell disease.
A 30-year-old member asked:

Can sickle cell disease kill you?

1 doctor answer3 doctors weighed in
Dr. Scott Diede
A Verified Doctor answered
A US doctor answered Learn more
Yes: In addition to infection, having sickle cell disease increases your risk of having a stroke, which sometimes can be fatal. Patients with sickle cell disease can also develop acute chest syndrome, a very serious condition requiring ICU care. Regular visits to a doctor who specializes in caring for patients with sickle cell can help reduce the likelihood of having these complications.
A 31-year-old member asked:

Is sickle cell disease dominant or recesive?

2 doctor answers3 doctors weighed in
Dr. Craig MacArthur
Pediatric Hematology and Oncology 34 years experience
Dominant genetically: Sickle cell disease is inherited as an autosomal recessive condition, which is what you will read from online sources and textbooks. One must inherit the gene from both parents to have the disease. This assumes that inheriting one copy of the gene (trait patient) has no phenotype (medical problems). This is not exactly true, as athletes have died from trait under extreme conditions.
A 39-year-old member asked:

Is sickle cell disease thromboembolic?

2 doctor answers2 doctors weighed in
Dr. Louis Cooper
Pediatrics 48 years experience
Rarely: Vaso-occlusive crises can be caused by decreased blood flow because of sickling. Slowing of circulation can be associated with blood clotting issues--all can be related to the sickled cells preventing blood cells to get through tiny blood vessels. Please ask your doctor to share additional info with you.

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Last updated Nov 28, 2017

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