A 29-year-old member asked:
can you still sickle cell if you're >3/4 white?
3 doctor answers • 5 doctors weighed in

Dr. David Escobar answered
Family Medicine 9 years experience
Yes: While sickle cell disease is most common in those of african, or african-american descent, one can still acquire the disease genetically based on their heredity.
5754 viewsAnswered >2 years ago

Dr. Alan Ali answered
Psychiatry 32 years experience
Sickle cell: Possible, need lab workup to confirm or rule our.
5754 viewsAnswered >2 years ago

Dr. James Ferguson answered
Pediatrics 46 years experience
Yes: If you have true SS disease you inherit a defective sickle cell gene from both parents. That means they both carried one defective gene ( in a pair tasked with making proper hemoglobin). It doesn't matter how far back in their family tree it started, or that it ever showed up before.
515 viewsReviewed >2 years ago
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Similar questions
A 42-year-old member asked:
What is sickle cell disease?
4 doctor answers • 8 doctors weighed in

Dr. Richard Chudacoff answered
Obstetrics and Gynecology 32 years experience
Abnormal blood cells: Sickle cell disease occurs when there is an abnormal type of hemoglobin in blood cells. Thought to be a survivor advantage against malaria, when these cells have too little oxygen they collapse and get stuck in small vessels. This cuts off the blood supply to organs and causes severe pain. Sickle cell traits is when only half the genes code for the abnormal hemoglobin, usually not symptomatic.
6632 viewsReviewed >2 years ago
A 52-year-old member asked:
Can you have partial sickle cell disease?
2 doctor answers • 5 doctors weighed in

Dr. Shabbir Hossain answered
Internal Medicine 16 years experience
Sickle cell trait: If you only have 1 of the two genes for sickle cell disease, you have sickle cell trait. This is a benign finding with no real symptoms. It's main significance is that you can pass this gene on to your children. If your partner also has sickle cell trait, then there is a probability that a child in the next gen will have sickle cell disease.
6108 viewsReviewed >2 years ago
A 30-year-old member asked:
Can sickle cell disease kill you?
1 doctor answer • 3 doctors weighed in

A Verified Doctor answered
A US doctor answered Learn more
Yes: In addition to infection, having sickle cell disease increases your risk of having a stroke, which sometimes can be fatal. Patients with sickle cell disease can also develop acute chest syndrome, a very serious condition requiring ICU care. Regular visits to a doctor who specializes in caring for patients with sickle cell can help reduce the likelihood of having these complications.
5306 viewsReviewed >2 years ago
A 31-year-old member asked:
Is sickle cell disease dominant or recesive?
2 doctor answers • 3 doctors weighed in

Dr. Craig MacArthur answered
Pediatric Hematology and Oncology 34 years experience
Dominant genetically: Sickle cell disease is inherited as an autosomal recessive condition, which is what you will read from online sources and textbooks. One must inherit the gene from both parents to have the disease. This assumes that inheriting one copy of the gene (trait patient) has no phenotype (medical problems). This is not exactly true, as athletes have died from trait under extreme conditions.
4898 viewsReviewed >2 years ago
A 39-year-old member asked:
Is sickle cell disease thromboembolic?
2 doctor answers • 2 doctors weighed in

Dr. Louis Cooper answered
Pediatrics 48 years experience
Rarely: Vaso-occlusive crises can be caused by decreased blood flow because of sickling. Slowing of circulation can be associated with blood clotting issues--all can be related to the sickled cells preventing blood cells to get through tiny blood vessels. Please ask your doctor to share additional info with you.
3890 viewsAnswered >2 years ago
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Last updated Nov 28, 2017
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