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A member asked:
Which causes more drowsiness - compazine (prochlorperazine) or zofran?
A doctor has provided 1 answer
Compazine (prochlorperazine) does...: Ondansetron (zofran), a powerful anti-nausea drug, is a serotonin 5-ht3 receptor antagonist. It blocks these "receptors" linked to the crtz..The "vomiting center" located in our brains. Compared to compazine, (prochlorperazine) a piperazine phenothiazine linked to other brain receptors (d2), it causes very little sedation. Both are used to decrease nausea and vomiting after surgery.
Answered 5/17/2021
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