A member asked:

Can ketoconazole cause your ankles to swell?

5 doctors weighed in across 2 answers

Possibly: It is possible if you are extremely allergic to ketoconazole, however, it is not likely to cause severe edema.

Answered 9/16/2013

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Allergic reaction.: Any medication can cause an allergic reaction in which swelling could be a possible outcome, especially if the swelling of the ankles occurred directly after taking the ketoconazole. I would consider discontinuing the medication.

Answered 9/29/2016

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