A 45-year-old member asked:
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does mtx and plaquenil (hydroxychloroquine) cause weight loss?

2 doctor answers
Dr. Ronald Krauser
51 years experience Rheumatology
No: Not unless they cause GI issues which Prohibit one from eating.
Answered on Jun 30, 2014
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Dr. Heidi Fowler
24 years experience Psychiatry
Weight loss: Methotrexate can lead to decreased appetite in 10 or more percent of people. However, as stated earlier weight loss would most likely occur if the person was having GI side effects like vomiting or diarrhea. Loss of appetite has been reported in 1% to 10% of people taking Hydroxychloroquine.
Answered on May 17, 2020

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