A member asked:

Why person who has g6pd deficiency can not handle stress?

6 doctors weighed in across 2 answers
Dr. Maulik Shah answered

Specializes in Clinical Genetics

Not necessarily true: G6pd deficiency is an inherited enzyme deficiency. The enzyme is involved in metabolism and anti-oxidant metabolism in red blood cells. Dietary triggers include fava beans and a variety of medications. Stress is not a well established trigger but it has been associated with worsening symptoms. In g6pd, red blood cells die due to the enzyme defect. As a result, stress can result in anemia.

Answered 11/5/2013

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Dr. Michael Engel answered

Specializes in Pediatric Hematology and Oncology

What stress are you: Referring to? G6pd deficiency predisposes patient to hemolytic crisis due to oxidant stress. This can come from many drugs eg., bactrm), foods (fava beans) and environmental exposures (naphthalenes). The oxidant stress that accompanies infections can also be problematic for these patients. Simple life stress should not be any more of an issue for a g6pd patient than it would be for a normal pt.

Answered 6/23/2015

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