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A 48-year-old member asked:

Is depression associated with low levels of neurotransmitter? which one?

2 doctor answers7 doctors weighed in
Dr. Lynne Weixel
Clinical Psychology 36 years experience
Some depression is: Serotonin plays an important role in feelings of well-being vs depression. Low levels can trigger depression and other disorders. Other neurotransmitters involved in depression include acetylcholine & catecholamines (dopamine, norepinephrine, & epinephrine). As well as corticotropin-releasing factor (crf), a stress hormone may be involved. But not all depression is chemically caused.
Dr. Robert Stewart
Clinical Psychology 44 years experience
Depression is a: Descriptive term for a set of symptoms. Although drugs that boost certain neurotransmitters are often helpful, there is little if any evidence that depression is caused by any neurotransmitter deficiency any more than a headache is cause by an Aspirin deficiency. Genetics, life circumstances & negative thinking patterns contribute to depression, but a precise cause is unknown.

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Last updated Jun 30, 2021

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