HealthTap Online Primary Care Doctors Accepting New Patients
Book a video visit
HealthTap
Telehealth
A member asked:

How much diphenhydramine hcl will kill me?

A doctor has provided 1 answer
Dr. John Chiu answered

Tons: You will likely be able to tolerate at least 5 capsules without much problem except for drowsiness and a dry mouth. As for the lethal dose, i don't know the exact number but i'd doubt that even taking 20 capsules can kill you.

Dr Parvez agreed

Answered 12/12/2020

4.9k views

Thank

Related Questions

A member asked:

Been taking diphenhydramine HCL for about 10 years in high doses. I have recently stopped taking them. The itching is intense. HOW CAN I STOP THE ITCH?

4 doctors weighed in across 2 answers

A member asked:

Is it okay to take a diphenhydramine HCl with my zanaflex (tizanidine)?

A doctor has provided 1 answer

A member asked:

Which is safer for long-term use? Doxylamine succinate or Diphenhydramine HCL?

A doctor has provided 1 answer

A member asked:

What are the dosage differences in diphenhydramine HCl and citrate if i take 50mg of HCl for sleep would i take 76 mg of citrate?

2 doctors weighed in across 2 answers

A member asked:

What side effects come from taking 1000mg of diphenhydramine HCL daily for 8 years?And how can I stop the itching after I've stopped taking them?

A doctor has provided 1 answer

Sponsored Content
HealthTap Medical Group does not endorse products or services. Sponsored content revenues support our mission to make health information free and accessible to all.Learn more

People also searched for:

Can diphenhydramine HCl 25 mg can kill you if you get an overdose?
Are fexofenadine HCl and diphenhydramine HCl the same?
Can diphenhydramine HCl show up in an at home drug test?
What should I take diphenhydramine HCl 25mg or diphenhydramine citrate 38mg?
I've been taking about 500 to 1400mg of OTC diphenhydramine hcl daily for about the last 6-8 years and have stopped. How can I stop the ITCHING!!?

Telemedicine

Primary Care
Manage Your Conditions
Women's Health
Children's Health
Men's Health
Senior Health
Wellness, Prevention & Lifestyle
Sexual Health
Mental & Behavioral Health
Travel Medicine
Urgent Care
Ask your question
Didn't find what you're looking for?

90,000 U.S. doctors in 147 specialties are here to answer your questions or offer you advice, prescriptions, and more.

Ask your question

More of what we treat

Allergies
Antibiotics
Asthma
High Blood Pressure
Prescriptions
Type 2 Diabetes
Content on HealthTap (including answers) should not be used for medical advice, diagnosis, or treatment, and interactions on HealthTap do not create a doctor-patient relationship. Never disregard or delay professional medical advice in person because of anything on HealthTap. Call your doctor or 911 if you think you may have a medical emergency.
HealthTap
HIPAA logo
HIPAASecure
Soc 2 Type 2 logo
SOC 2 Type 2Certified
JCAHO Accredited
JCAHOAccredited
Member App

Download HealthTap

Video visit and message your doctor

Member App QR Code
Play Store Member LinkApp Store Member Link

Questions?

+1 (888) 828-0841support@healthtap.com
LinkedInTwitter
HomeTermsPrivacyCookiesDMCAHealth TopicsDoctors DirectoryDoctor Q&A by Specialty
Copyright 2026 HealthTap, Inc.