A member asked:

Are fexofenadine hcl and diphenhydramine hcl the same?

A doctor has provided 1 answer

No: Benadryl (diphenhydramine) is a short-acting antihistamine and is more likely to make you sleepy when used. Fexofenadine is a second-generation, non-sedating antihistamine which should have more lasting effects, closer to 24 hours, and is less likely to make you sleepy.

Answered 6/5/2019

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