A member asked:

C3 196 which is high. c4 is 33.7. ana +1:320. any autoimmune can cause c3 to be high? rheumy is testing for hashimoto's thyroiditis. could this be?

4 doctors weighed in across 2 answers

Autoimmune disease: Hashimoto's won't make these changes. Has to be something else. Without further history and physical, it's essentially impossible to make a diagnosis off a few abnormal blood tests.

Answered 9/11/2013

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See below: ANA disorders such as lupus have low complement level, but nonspecific inflammation can raise complement levels such as infection or other autoimmune disorders.

Answered 6/10/2014

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