Are zoloft (sertraline) and luvox the same?

Not exactly: They are both ssri medications for depression. However, they have different chemical make ups and groups that respond to the medication.

No: Sertraline (Zoloft/ Lustral) is an SSRI which is FDA approved for the treatment of major depressive disorder, panic disorder, social anxiety disorder, post traumatic disorder, obsessive compulsive disorder, premenstrual dysphoric disorder and body dysmorphic disorder. Luvox (Fluvoxamine) is approved by the FDA for the treatment of obsessive compulsive disorder. However, it has been used off-label