A member asked:

Should i take cymbalta (duloxetine) in the morning or evening?

3 doctors weighed in across 2 answers
Dr. Alan Ali answered

Specializes in Psychiatry

Cymbalta (duloxetine): Some sedation is expected at higher dosage. Best to take main dose in evening.

Answered 1/17/2021

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Whichever works best: You may take it whichever way works best for you. Take it in the evening if it makes you tired or in the morning if it keeps you awake or you could divide the dose to a twice daily dosage if you would like. Please discuss it with your psychiatrist however before making any changes.

Answered 9/12/2013

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