Can dihydrotestosterone cause high psa levels?

PDA testosterone: Psa is protein secreted by prostate testosterone including metabolizes like digudrotestosterone control prostate function and size hence use of Dht will increse psa and hence it's use should be monitored by your md.

Yes?: Dihydrotestosterone (dht) is the bio-active form of testosterone(t). Blocking t to Dht by 5-alpha reductase inhibitors such as Finasteride or Dutasteride will decrease psa by some 50%. So, we can say more Dht may cause psa elevation. But, still remember, to a great extent, a healthy body has all bio-feed-back automation to regulate the balance of substances of metabolism. Then, if any, high dht...

Unlikely: Though there may not be a consensus on the correct answer, this issue was assessed in a study (2010) where 114 healthy men older than 50 years without known prostate disease were randomly assigned to receive transdermal Dht (70 mg) or placebo gel daily for 2 years. At the end of two years, vs placebo, despite a 10-fold increase in serum dht, there was no increase in either prostate volume or psa.