A member asked:

Should i be concerned about high psa levels?

13 doctors weighed in across 4 answers

Yes, get checked.: If this is your first result showing high blood psa, you should see your doctor to get worked up to be sure it isn't prostate cancer. Other things, like prostate hypertrophy, can give high psa, but there are different results on dre (digital rectal exam) than cancer. The prostate would be firm, smooth, and rubbery, not rough and irregular. But you don't know unless you get checked, so see dr.

Answered 10/17/2018

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Maybe.: Positive predictive value of psa test between 4 and 10 is about 25%. Above 10 is about 50%. That means 3 out of 4 men with psa between 4 and 10 will not have cancer. If over 75 risk of dying from newly diagnosed cancer identified by psa testing is very low. So, wouldn't be worried. Should have had this conversation before testing... Psa test not recommended without understanding implications.

Answered 11/7/2019

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Dr. Darren Mack answered

Specializes in Urology

Yes: Psa, or prostate specific antigen, is a protein manufactured by glands in the prostate. It is made by both malignant and non-malignant cells in the prostate and its value in your blood can vary with the overall size of the prostate, presence of glandular hyperplasia, or bph, prostate cancer, and any infections or inflammatory conditions in the prostate. A prostate biopsy is the next best step.

Answered 10/3/2016

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Dr. James Lin answered

Yes, ...: A 50-yr man with no clinical or lab suspicion or documentation for UTI should concern his high psa. But question is if you need to have biopsy right away. Answer is no; the significance of a solitary psa should be coordinated with fh of p-ca, finding of digital rectal exam (dre), etc. If high + uneven consistency of prostate on dre, you should have prostate us + biopsy right away. Detail? Ask doc.

Answered 1/14/2019

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