A member asked:

Cause of exostosis on tmj...10 year on fosamax (alendronate)?

8 doctors weighed in across 3 answers
Dr. Peter Karsant answered

Specializes in Dentistry

TMJ: Exostosis is an outgrowth of cartilaginous tissue on bone. Fosamax (alendronate) is to maintain bone. Don't think the two are related. You should have a test to see if your bone levels are stable (you had a baseline test right?) and if so you can go off the Fosamax (alendronate) as it has a half life of 13.5 yrs. Once off you should get test yearly and if levels are stable great if not you can go back on the drug. See md.

Answered 11/28/2017

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TMJ Exostosis: I'm not aware of any literature that suggests that bisphosphonates such as Fosamax (alendronate) can lead to exostoses of the tmj. Usually we see TMJ exostoses as a result of trauma or arthritis. You don't describe any symptoms. Have you had an MRI or a ct? Usually these are diagnostic. An exostosis that is asymptomatic requires no treatment. You should see an oral and maxillofacial surgeon in consultation.

Answered 3/18/2015

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Dr. Louis Gallia answered

Specializes in Surgery - Oral & Maxillofacial

Not due to fosamax (alendronate): I know of no data to suggest a relationship between fosamax (alendronate) and TMJ disorders. See an oral surgeon who specializes in TMJ surgery.

Answered 3/18/2015

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