I take wellbutrin (bupropion) and an ssri, but don't want the ssri anymore. can i take wellbutrin (bupropion) with a natural supplement like st. john wort, sam-e, or other?

Possibly: These are all reasonable and intelligent possibilities. You must discuss your treatment options with your doctor and come up with a plan together.

Talk w/ your Dr!: It is not unusual to feel dissatisfied with ssri treatment. But, you absolutely must taper off with your doctors assistance to avoid the very real problems that can come with abrupt discontinuation. I hope your dr cooperates, but if not - find another - do not do it yourself! ok? It might be possible to get free of meds entirely but be patient - you'll learn how to handle these issues with help.

SSRIs: Several viable options exist, but please discuss with your prescribing physician first.