A member asked:

Can methotrexate be taken for long periods of time safely? for example years.

6 doctors weighed in across 2 answers
Dr. Ramachandran Srinivasan answered

Specializes in Rheumatology

Arthritis: Yes it can in small doses. Your doctor will be monitoring side effects and toxicity which are defendant upon dose, duration etc. Consult with your doctor.

Answered 1/26/2021

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Yes: I have some patients who have been on Methotrexate for over 25 years without any issues.

Answered 4/1/2023

4.9k views

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