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A 40-year-old female asked:

Is it safe to take fluoxetine and propranolol hydrochloride sr together?

2 doctor answers4 doctors weighed in
Dr. Robert Pearson-Martinez
Pediatric Cardiology 21 years experience
Caution advised: Will need to monitor heart rate, BP & electrolytes. Taking them together may increase the beta blocker (propranolol) levels --> may increase risk of lower bp, lower hr, heart block there may also be increased risks of lower sodium levels or SIADH (excessive anti diuretic hormone secretion which may cause fluid retention). Generally recommended to monitor closely or consider other tx alternatives.
Created for people with ongoing healthcare needs but benefits everyone.
Dr. Shariq Refai
Psychiatry 14 years experience
Can interact: Fluoxetine can increase the affects of propranolol. So it depends on the dose used. It can be used safely together under the supervision of your physician taking that into consideration the dose may need to be adjusted.
Created for people with ongoing healthcare needs but benefits everyone.
Last updated May 24, 2019

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