How long does it take for nasonex (mometasone) to work on nasal turbinate swelling?

Days: It may start working in 12 hrs but optimal effects will be at 5 to 7 days with regular usage.

Couple days: You should start to see improvement in 1-2 days and it will gradually build with continued use. By 2 weeks, efficacy should be up to 80% and by 4 weeks, nearly 100%. That's why its so important to use it regularly, because it doesn't work that great if only used intermittently "as needed.".

Nasonex (mometasone): Nasonex (mometasone) is a topical steroid that helps to reduce turbinate hypertrophy. It takes several weeks of daily use before one noses any improvement.