Applyi histofreeze directly in skin for warts, is swallow and red burning, is that normal?

Histofreeze: Warnings and precautions: depigmentation of skin is a potential side-effect and may be considered cosmetically unacceptable, particularly with more highly pigmented skin types. Undesirable effects: a stinging or painful sensation during and after freezing, which will rapidly fade away after the thawing phase. Changes in the intensity of pigmentation may occur.

Yes: Though you froze the area it creates a burn and redness and pain is not unusual.