U.S. doctors online nowAsk doctors free
Southfield, MI
A 24-year-old female asked:

Dx'ed w/ narcolepsy/hypersomnia, have a substance abuse history pre-diagnosis. provigil and nuvigil don't help eds. what else to try before amphetamines?

2 doctor answers7 doctors weighed in
Dr. Alvin Lin
Geriatrics 32 years experience
Xyrem: Talk to your sleep specialist about xyrem (sodium oxybate = http://www.Xyrem.Com/) which is tightly controlled for cataplexy, narcolepsy & excessive daytime sleepiness (eds). Do some research on this drug (http://goo.Gl/djex1d & http://www.Fda.Gov/drugs/drugsafety/ucm332029.Htm). Do not take this drug (xyrem) w/alcohol (you don't drink) or any other drug that affects breathing.
Created for people with ongoing healthcare needs but benefits everyone.
Dr. Ravi Chand
Psychiatry 28 years experience
Narcolepsy: amphetamines – sympathomimetics - avoid in patients with heart disease, hypertension, arrhythmias. Can cause sudden death. Do ekg first. – potential for anxiety, psychosis, mania – may disrupt sleep – rebound hypersomnia common – moderate abuse potential • modafinil, armodafinil – interferes with birth control pills – rare stevens-johnson syndrome or other severe rash – sometimes less potent tha.
Created for people with ongoing healthcare needs but benefits everyone.
Last updated Aug 27, 2013


Content on HealthTap (including answers) should not be used for medical advice, diagnosis, or treatment, and interactions on HealthTap do not create a doctor-patient relationship. Never disregard or delay professional medical advice in person because of anything on HealthTap. Call your doctor or 911 if you think you may have a medical emergency.