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Southfield, MI
A 24-year-old female asked:

Dx'ed w/ narcolepsy/hypersomnia, have a substance abuse history pre-diagnosis. provigil and nuvigil don't help eds. what else to try before amphetamines?

2 doctor answers7 doctors weighed in
Dr. Alvin Lin
Geriatrics 31 years experience
Xyrem: Talk to your sleep specialist about xyrem (sodium oxybate = http://www.Xyrem.Com/) which is tightly controlled for cataplexy, narcolepsy & excessive daytime sleepiness (eds). Do some research on this drug (http://goo.Gl/djex1d & http://www.Fda.Gov/drugs/drugsafety/ucm332029.Htm). Do not take this drug (xyrem) w/alcohol (you don't drink) or any other drug that affects breathing.
Dr. Ravi Chand
Psychiatry 27 years experience
Narcolepsy: amphetamines – sympathomimetics - avoid in patients with heart disease, hypertension, arrhythmias. Can cause sudden death. Do ekg first. – potential for anxiety, psychosis, mania – may disrupt sleep – rebound hypersomnia common – moderate abuse potential • modafinil, armodafinil – interferes with birth control pills – rare stevens-johnson syndrome or other severe rash – sometimes less potent tha.
Last updated Aug 27, 2013

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