A 55-year-old female asked:
been on provigil for narcolepsy for 10yrs are then any studies for possible problems with long term use?
2 doctor answers
Dr. Bennett Machanic answered
51 years experience Neurology
Unlikely: Most patients on Provigil do very well without any long-term problems. Always prudent to periodically check liver fnctns and blood count just in case, but unlikely any issues. Also, positive is fact that tolerance with Provigil is rather uncommon, so doseage can stay stable.
Answered on Jun 30, 2014
Dr. Michelle Zetoony answered
17 years experience Sleep Medicine
Usually not: Overall a very safe medication, long term usage has not been fully studied. The thought is that it works through Dopamine pathways, so some long term effects can be on this system. Neurologic function and mood disturbances have been reported side effects of long term usage.
Answered on Jun 25, 2014
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