No luck with lexapro, is effexor (venlafaxine) a good second choice for treating depression and anxiety in a 22 year old in good health otherwise?

Many possibilities: There are many antidepressants from which to choose. Recent studies suggest that just because 1st drug from a family doesn't work doesn't mean that you need to switch drug families. Also, we can't say a drug didn't work unless you couldn't tolerate the highest dose. Lexapro (escitalopram) is a member of ssri family of which there are many. Talk to your doc about all your options (sometimes dictated by insurance).

Lexapro (escitalopram): Switching from an ssri to an snri, if the Lexapro was given at optimum dose for sufficient time with not enough clinical response, is a possibility which needs tobe reviewed with your doctor. Another option is augmenting Lexapro with another medicine such as abilify (aripiprazole).