6 weeks: Depending upon the reference, we usually suggest taking any given levothyroxine dose for at least 6wks prior to (re)checking your tsh. Make adjustments as necessary & then recheck again in another 6wks. While most labs use 0.45 to 4.5 as normal reference range, many specialists aim for somewhere between 1-2 as long as you're feeling good w/o side effects.
Answered 2/3/2015
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If you change: To the correct level, it will take 4-6 weeks to reequilibrate. Make sure you're on brand name T4 replacement, as the generics are unreliable and levels can vary from one month to the next.
Answered 4/1/2023
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