Are there any side effects to taking pancreatic enzyme supplements?

Yes: Like all medicines, pancreatic enzymes can produce side effects such as diarrhea, pain, bloating. Only take medications if needed and under the supervision of a physician.

Yes for some...: Virtually all supplements have possible side effects. Most people tolerate pancreatic enzymes well but people with gastritis/ sensitive stomachs often will experience stomach pain/irritation from taking protease enzymes that are included in most enzyme supplements. Some people may get loose stools from enzymes. It is also possible to react to fillers/binders/additives in any med or supplement.