A member asked:

Does taking a few grams of melatonin create a hangover effect the next day? feel fatigued from sleep deprivation but got some sleep from melatonin 4g

3 doctors weighed in across 2 answers

Sometimes: Everyone is different. Some people are more sensitive than others. The dose that is " just right " for you may be different and what works for you may cause a hangover in others. Use the lowest does that seems to work along with good sleep hygiene. The smaller the dose the less likely to have a problem.

Answered 9/8/2016

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People vary: But the usual dose for melatonin is 0.3 to 5 mg per dose. Have you really been taking 4 grams/dose or did you mean mg? Yes it can cause a hangover in some people, particularly when they're on other drugs like you are.

Answered 7/12/2013

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Why is 300mg of melatonin not making me tired enough to sleep properly?

3 doctors weighed in across 2 answers