Fatigue & activity..: Intolerance stem from oxygen delivery to the tissues inadequate to meet the demands of those tissue under load. Oxygen is delivered to tissues bound to hemoglobin, which is packaged into red cells so that blood viscosity is low enough to permit flow through the smallest vessels (capillaries). Oxygen is needed for us to generate energy by oxidative metabolism. Not enough oxygen = decreased energy.
Answered 10/1/2017
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