A member asked:

Celiac. b12 serum high and increasing despite no vitamins (per doc). muscles burn, legs weak, confused. 'functional' b12 defi possible? doc stumped.

A doctor has provided 1 answer

MTHFR, iron, celiac: Could be a B12 metabolism error. Check mthfr dna and replace with methyl b12, pyridoxal-5-phosphate, l-methyl folate (folic acid). Bloodwork is only testing Cyanocobalamin - inactive form which is accumulating apparently. Also check iron studies and zinc levels due to celiac, and add multi b since fortified wheat is out.

Answered 4/17/2019

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