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A member asked:

Can you die from thrombotic thrombocytopenia purpura?

2 doctor answers6 doctors weighed in
Dr. Liawaty Ho
Hematology and Oncology 23 years experience
YES: Unfortunately, yes. People can die from ttp. They can develop seizure, coma, renal failure, cardiac hemmorhage/bleeding, sudden cardiac arrest, myocardial infarction etc. Need to get treatment as soon as possible.
Dr. Ritesh Rathore
Hematology and Oncology 30 years experience
agre absolutely... fortunately modern treatments are effective in 80-90% cases.
Mar 6, 2012
Dr. Keith Stockerl-Goldstein
Hematology and Oncology 30 years experience
Yes: This can be a life-threatening condition. It should be treated by a physician experienced in the disorder, generally a hematologist.

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A 40-year-old member asked:

What is the disease ?Thrombotic thrombocytopenia purpura?

1 doctor answer1 doctor weighed in
Dr. Gurmukh Singh
Pathology 49 years experience
Abnormal platelet: Function due to deficiency of a metaloproteinase. Deficiency, usually acquired, of an enzyme that breaks down large multimers of von willebrand factor causes overactivation of platelets leading to intravascular microthrombi that affect the functions of the kidneys, brain, lungs and other organs. It can be treated by transfusing normal donor plasma.
A 31-year-old member asked:

Most common symptoms of thrombotic thrombocytopenia purpura?

2 doctor answers2 doctors weighed in
Dr. Liawaty Ho
Hematology and Oncology 23 years experience
TTP: Most common symptoms would be headache and fatigue- however one can be presented with different kind of neurological problems- including confusion, shaking/involuntary movement etc that is caused by the ttp. The most common sign -off course is low platelet.
CA
A 28-year-old male asked:

What is the definition or description of: thrombotic thrombocytopenia purpura?

1 doctor answer2 doctors weighed in
Dr. Michael Dugan
Specializes in Hematology
TTP is a serious: Medical condition in which the platelets form clots within the small blood vessels throughout the body. Patients usually come to attention due to low HGB or platelets, but also may have fever, kidney insufficiency, seveer headache, and even seizures and stroke. This is an absolute medical emergency.
A 33-year-old member asked:

How common is it for somebody to get thrombotic thrombocytopenia purpura?

1 doctor answer4 doctors weighed in
Dr. Ritesh Rathore
Hematology and Oncology 30 years experience
Rare disease: This is a rare but life-threatening disease; approx 2-3 cases per 100,000 population in the USA are seen.
A 37-year-old member asked:

What is the treatment for thrombotic thrombocytopenia purpura?

1 doctor answer1 doctor weighed in
Dr. Gurmukh Singh
Pathology 49 years experience
Plasma transfusion: Ttp is due to deficiency of an enzyme normally present in blood. This enzyme controls the activation of platelets. The deficient enzyme is usually replaced by transfusing plasma and in severe cases by exchanging the patient's plasma with normal plasma.

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