A member asked:

Difference between idiopathic thrombocytopenia purpura and thrombotic thrombocytopenia purpura?

2 doctors weighed in across 2 answers
Dr. Dominic Riganotti answered

Specializes in Infectious Disease

Its Complicated: Itp; history of viral illness, associated with lymphoma, cll, hiv, connective tissue diseases (no splenomegaly or megakaryocytes) chronic and insidious course in adults, ttp (pneumonic: fat registered nurse) fever, anemia, thrombocytopenia, renal involvement, neurologic involvement itp treatment : steroids / Prednisone / ivig / Rhogam with possible splenectomy ttp ....... Plasmapheresis.

Answered 7/1/2014

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Dr. Michael Dugan answered

Specializes in Hematology

The are completely: Different. Itp is the autoimmune destruction of platelets and is managed with immunosuppression - the first line is usually prednisone. Ttp is the microvascular consumption of platelets (small clots). This can be associated with anemia, renal failure, ha and fever. It is a medical emergency and is managed with plasma exchange.

Answered 9/22/2013

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Is thrombocytopenia purpura as the same as blood dyscrasia?

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