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A member asked:
Rxd topamax, xanax, abilify (aripiprazole). topa induces 3a4. i love white grapefruit juice, which inhibits 3a4. is this an unsafe combo esp with the topamax..?
A doctor has provided 1 answer
Confusing: Topomax is a weak inducer of cyp 3a4, and maybe c19. Your biggest issue here is the grapefruit juice, which inhibits 3a4 quite significantly. This could increase the effects of both xanax and abilify (aripiprazole). Either you need to stop the grapefruit juice or drink it at a constant level. Please inform your prescribing psychiatrist about this.
Answered 7/7/2013
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