Does gallbladder cancer appear as acalculous gallbladder wall thickening?or as a specific area with scar like appearance?

Gallbladder cancer: Is so rare that there is no typical presentation. It is usually found incidentally on a gallbladder specimen that was removed for stone or infection.

Porcelain: The finding of a "porcelain gallbladder" on x-ray raises the suspicion for cancer; however, not diagnostic for cancer. Gallbladder cancer can present with symptoms and findings similar to patients with routine gallstones: right upper quad. Pain after eating with an ultrasound showing a thickened wall and stones. Most patients with acalculous cholecystitis, do not have cancer but still need surgery.

Not necessarily: Gallbladder cancer can occur with or without stones. Risk factors include porcelain (calcificed wall) gallbladder, when stones > 3 cm in size are present, large polyps, certain infections, and congential anomalies of the bile duct.