A member asked:

Is it true that many of us have the genetic marker for ankylosing spondylitis but will never have any symptoms?

A doctor has provided 1 answer

See below: Over 90% who tested positive for seronegative spondyloarthropathy never have any symptoms. However you have previously posted that you have had 2 cases of iritis---so technically you have had symptoms. Hla-b27 can be seen in all seronegative spondyloarthritis which is a family of arthrititic conditions include psoriatic, chrohn's, ulcerattive colitis, reactive/reiter's as well as ankylosing spon.

Answered 6/26/2013

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