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A member asked:
Had a methotrexate injection yesterday after finding out there is still tissue left after a d&c was told not to take or eat food high in folic acid why is this?
6 doctors weighed in across 2 answers
Taking folic acid at: The same time that Methotrexate is given lessens the effectiveness of the latter because of the competition for the binding on the same enzyme -dihydrofolate reductase- thus lessening its effectiveness. God bless you! http://arthritis.about.com/od/arthritismedications/ss/arthritis_drugs_2.htm. http://www.livestrong.com/article/420615-why-cant-i-take-folic-acid-the-same-day-as-methotrexate/.
Answered 6/28/2014
5k views
Correct advice: Methotrexate works by inhibiting folic acid's actions in the body. If you take excess folic acid, the Methotrexate may not work.
Answered 6/28/2014
5k views
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If methotrexate were taken along with folic acid does it have the same side effect of just taking methotrexate?
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