Had a methotrexate injection yesterday after finding out there is still tissue left after a d&c was told not to take or eat food high in folic acid why is this?

Taking folic acid at: The same time that Methotrexate is given lessens the effectiveness of the latter because of the competition for the binding on the same enzyme -dihydrofolate reductase- thus lessening its effectiveness. God bless you! http://arthritis.about.com/od/arthritismedications/ss/arthritis_drugs_2.htm. http://www.livestrong.com/article/420615-why-cant-i-take-folic-acid-the-same-day-as-methotrexate/.

Correct advice: Methotrexate works by inhibiting folic acid's actions in the body. If you take excess folic acid, the Methotrexate may not work.